Abstract

Bone mass was measured by digital image processing method in 114 X-ray hand films of 57 Turner's syndrome, in comparison with 120 normal and 5 hypopituitary female sujects. The cross-sectional mean bone mass of untreated Turner's syndrome aged 12–14 years and 14–16 years was 1.65±0.26 and 1.82±0.18 mm aluminum (Mean±SD), respectively. These are significantly lower (P<0.01) than those (1.94±0.29 and 2.28±0.25) for normal female children of the same chronological age. When the mean bone mass is obtained according to the bone age, that of Turner's girls (6 to 16 years) did not differ from that of the controls. The mean bone mass (2.36±0.27) of 14 adult Turner's patients (23.7±2.4), who had been given sex hormone since 16 years of age, was significantly (P<0.001) lower than that (2.74±0.17) of 21 normal female age-matched subjects.

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