Bone Marrow Injection for Treatment of Aneurysmal Bone Cyst

Abstract

Study design: Patients had Aneurysmal bone cyst lesion that underwent to be treated by Injection of Autologous Bone Marrow Aspirates (ABM) and follow up of this case for the final results. Patients and Methods: Sixteen patients had had Aneurysmal bone cyst had been treated by ABM injections. Study have 16 patients 11 females (68.75 %) and 5 male (31.25 %). Age ranged from 3-14 years with average age 7.5 years. Number of injections for every patient ranged from 2-6 times with average 4.4 times. This study including 5 cases (31.25 %) with proximal femoral cyst, 9 cases (56.25 %) had tibial cyst (2 distal and 7 proximal tibiea) and 2 cases (12.5 %) had proximal humeral cyst. All patients treated by injection of Autologous Bone Marrow Aspirates which obtained from the iliac crest. The bone marrow aspirates was obtained percutaneous by bone marrow aspiration needle, According to follow up X-ray during injections we decide continuity of injections. Average size of the defect was 2.3 cm. and average amount bone marrow/inj. Was 10.2 cc. Results: Pain Score according to VAS ranged from 3-9 with average 5.7 which was improved to average 1.5 at final follow up. Healing time ranged from 21 - 90 days with average 42.2 days. Motion of the arm as patients can move their arm without pain was allowed. Weight bearing for the lower limbs also had been allowed as patients felt pain subsided even there is no complete healing radiological. Conclusion: Aneurysmal Bone cyst has risk for fracture and recurrence after various modalities of treatment. Bone marrow has the advantage of percutaneous treatment (minimal Invasive) and has no recurrence reported for the current study.