Abstract
Background: Chronic kidney failure treated by chronic dialysis and kidney transplantation is characterised by disorder of bone metabolism and high or low bone turnover, resulting in osteopenia/osteoporosis and increased fracture risk. Measurement of bone markers enables indirect insight into the rate of bone remodeling and its changes in the course of disease. In this study bone formation and bone resorption markers were measured in patients on chronic hemodialysis treatment and in kidney transplant recipients with regard to specific risk factors of this metabolic bone disorder, i.e. parathyroid hormone levels (PTH), age, sex, hemodialysis duration and post-transplant period.
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