Abstract
• Posphate-crosslinked sodium alginate-based hydrogels was developed. • The hydrogels show interconnected porous networks. • The hydrogels show excellent bone-like apatite formation ability. Bioactive materials exhibiting bone-like apatite formation are crucial for inducing the osteogenic potentials of bone cells in the bone tissue engineering field. Herein, we report the design and synthesis of bioactive phosphate-crosslinked sodium alginate-based (PSA) hydrogels for biomineralization using a calcium-free approach. The hydrogels produced contained interconnected porous networks and exhibited improved swelling and biodegradable properties with excellent bone-like apatite formation abilities under simulated body fluid (SBF) conditions, which were attributed to the presence of phosphate groups. The devised functional phosphate-crosslinked sodium alginate hydrogels provided potential scaffolds for bone tissue engineering applications.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
