Abstract

cover a broad range of clinical situations that pre-dispose the patient to bone deficit, such as criticalcare, prolonged parenteral nutrition (PN), treat-ment in rehabilitation programs, and patients withestablished osteoporosis. Many of the articles alsoincorporate state of the art recommendations tooptimize vitamin D and calcium status.The critical role of vitamin D and calcium inbiologic states other than bone metabolism is dem-onstrated in reports on the role of vitamin D incancer and immunity

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