Abstract
BackgroundSuboccipital craniectomy is a conventional approach for exploring cerebellopontine angle lesions. A variety of techniques have been successfully employed to reconstruct a craniectomy. This is the first report about the histological findings after performing a cranioplasty by using a mixture of autologous bone chips and human allogenic fibrin glue.Case presentationA 53-year-old German woman underwent left lateral suboccipital retrosigmoidal craniectomy for treatment of trigeminal neuralgia in 2008. Cranioplasty was perfomed by using a mixture of autologous bone chips and human allogenic fibrin glue. Due to recurrent neuralgia, a second left lateral suboccipital craniectomy was performed in 2012. The intraoperative findings revealed a complete ossification of the former craniotomy including widely mature trabecular bone tissue in the histological examination.ConclusionA mixture of autologous bone chips and human allogenic fibrin glue seems to provide sufficient bone-regeneration revealed by histological and neuroradiological examinations.
Highlights
Suboccipital craniectomy is a conventional approach for exploring cerebellopontine angle lesions
Cranioplasty using a mixture of autologous bone chips and human allogenic fibrin glue is a well known technique first reported in 1997 by Sawamura et al We report a case of a patient using this technique in 2008 with a surprising intraoperative and histological result
The present case demonstrates that a stand-alone implantation of a fibrinogen and thrombin mixture seems to provide sufficient bone-regeneration revealed by histological and neuroradiological examinations
Summary
A mixture of autologous bone chips and human allogenic fibrin glue seems to provide sufficient bone-regeneration revealed by histological and neuroradiological examinations.
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