Abstract
Fat-soluble ligands like steroid hormones exert their actions through nuclear receptor-mediated transcriptional controls. Nuclear receptors are hormone-dependent transcription factors, and their ligand-dependent function is facilitated by transcriptional co-regulators, that were initially considered to bridge nuclear receptors with transcription initiation complex. However, recent progress in epigenome and chromatin research has uncovered that hormone-dependent transcriptional controls by nuclear receptors require a number of epigenetic/transcriptional co-regurators facilitating chromatin reorganization.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
