Body weight in patients with cardiovascular dysfunction in arterial hypertension

Abstract

Objective - analyzed the performance of the structural remodeling of the myocardium and vascular endothelial function in patients with hypertension and varying body weight after the 3-6 month antihypertensive (lisinopril, amlodipine) and lipid-lowering (atorvastatin) therapy.Material and methods. We studied 87 patients with essential hypertension (EH) II stage chronic heart failure (CHF) and 0-stage I-II functional class (FC) aged 60 to 88 years (average age was (77.3 + 0.8) years). The diagnosis of GB was made in accordance with the methodological recommendations of the Ukrainian Association of Cardiologists for the prevention and treatment of hypertension (2008). All patients receiving combination antihypertensive (ACE - lisinopril 10 mg 1 time / day, AK - amlodipine 5 mg 1 time / day) and hypolipidemic (atorvastatin 10 mg 1 time / day) therapy.Results of the study show that the smallest dynamics of left ventricular hypertrophy regression and improvement of the vessels endothelial function is determined in patients with deficiency of body weight.