Abstract
To the Editor.— The findings reported by O'Sullivan inThe Journal(1982; 248;949) that body weight in patients with normal gestational glucose tolerance test results is not related to diabetes have a serious flaw. With only 66 obese subjects in the normal control group, the author had only a 12% chance to detect a relationship between relative weight and diabetes. Therefore, it is not surprising that no relationship was found. This low chance of detection is based on the assumption that obese patients have a relative risk of 1.82 for diabetes. This assumption was obtained using the women who had previous transient gestational glucose intolerance. The incidence of diabetes in the obese women in this group (46.7%) was divided by the incidence of diabetes in the nonobese group (25.6%). Therefore, if obesity confers a risk of 1.82 for diabetes, there is a 88% chance that this risk level (or lower)
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