Abstract

The objective of this study is to evaluate the association between body mass index (BMI) and migraine in general population Chinese cohort. This was a cross-sectional secondary analysis from a general population Chinese cohort of men and women of reproductive and post-reproductive age ranging between 18 and 65 years. Migraine was defined utilizing ICHD criteria. Body mass indices were calculated using measured height and weight and categorized based on the World Health Organizations criteria. The 1-year period prevalence of migraine was 9.3 %. No association was identified between migraine and those with a BMI < 30.0. Compared to those with normal BMI (18.5–23.0), those with BMI ≥ 30 (morbid obesity) had a greater prevalence of migraine (8.6 vs. 13.8 %, p = 0.000). Multivariate-adjusted odds ratio demonstrated that those with morbid obesity had a greater than twofold increased odds of migraine [OR 2.10 (1.39–3.12)] as compared to those with a BMI between 18.5 and 23.0. No association was found between obesity and migraine severity, frequency, or disability. Morbid obesity was associated with twofold increased odds of migraine in this Chinese men and women cohort of predominantly reproductive age.

Highlights

  • Obesity is a major medical and public-health problem worldwide, affecting virtually all age and socioeconomic groups

  • The objective of this study is to evaluate the association between body mass index (BMI) and migraine in general population Chinese cohort

  • We found a link between obesity and migraine prevalence rather than severity, frequency or disability

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Summary

Introduction

Obesity is a major medical and public-health problem worldwide, affecting virtually all age and socioeconomic groups. Its prevalence is constantly increasing throughout the world [1, 2], and it threatens to overwhelm both developed and developing countries. In China, obesity, defined as body mass index (BMI) C23.0 kg/m2, affects almost half (44.6 %) of the adult population among adults age 40 years and above (men: 46.4 %; women: 43.6 %) [3]. Migraine is a major public-health problem worldwide, less well recognized. In China, its prevalence in adults is 9.3 % (men: 5.9 %; women: 12.8 %) [4], and it causes substantial illness and disability.

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