Abstract
Background Evidence regarding the relationship between body mass index (BMI) and 1-year unplanned readmission was limited. Therefore, the objective of this research is to investigate whether BMI was independently related to 1-year unplanned readmission in Chinese patients with acute myocardial infarction (AMI) after percutaneous transluminal coronary intervention (PCI) after adjusting for other covariates. Methods The present study was a cohort study. A total of 214 participants with AMI after PCI were involved in a hospital in China from 1st January 2017 to 1st January 2018. The target independent variable and the dependent variable were BMI measured at baseline and 1-year unplanned readmission, respectively. Covariates involved in this study included age, gender, TC, triglyceride, HDL-C, LDL-C, PT, APTT, INR, creatinine, HGB, LVEF, discharge medication, marital status, educational level, COPD, diabetes mellitus, heart failure, history of ischemic stroke, history of hemorrhagic stroke, arrhythmia, and hypertension. Results The average age of 172 selected participants was 60.2 ± 10.8 years old, and about 68.6% of them was male. The rate of readmission in patients with AMI was 26.14%. The result of fully adjusted binary logistic regression showed BMI was negatively associated with risk of readmission after adjusting confounders (hazard ratio (HR) = 1.1, 95% CI 0.93–1.29). Nonlinear relationship was detected between BMI and 1-year unplanned readmission, whose point was 29.3. The effect sizes and the confidence intervals of the left and right sides of inflection point were 0.9 (0.7–1.2, P for nonlinearity = 0.530) and 2.8 (1.3–5.8, P for nonlinearity = 0.530) and 2.8 (1.3–5.8, Conclusion BMI has a nonlinear relationship with 1-year unplanned readmission in patients with myocardial infarction. The 1-year unplanned readmission rate of overweight patients (BMI > 29.3 kg/m2) has increased significantly. Obesity paradox does not exist in terms of readmission of Chinese patients with myocardial infarction after PCI.
Highlights
Evidence regarding the relationship between body mass index (BMI) and 1-year unplanned readmission was limited. erefore, the objective of this research is to investigate whether BMI was independently related to 1-year unplanned readmission in Chinese patients with acute myocardial infarction (AMI) after percutaneous transluminal coronary intervention (PCI) after adjusting for other covariates
No statistically significant differences were detected in age, gender, total cholesterol (TC), low-density lipoprotein C (LDL-C), prothrombin time (PT), international normalized ratio (INR), creatinine, left ventricular ejection fraction (LVEF), discharge medications, educational level, chronic obstructive pulmonary disease (COPD), diabetes mellitus, heart failure, history of ischemic stroke, history of hemorrhagic stroke, arrhythmia, and hypertension among different BMI groups. e subjects were divided into three equal parts according to the distribution of BMI. e BMI of the first group, the second group, and the third group was
By univariate binary logistic regression, we found that gender, TC, triglyceride, highdensity lipoprotein C (HDL-C), LDL-C, PT, activated part of prothrombin time (APTT), INR, creatinine, HGB, LVEF, discharge medications, COPD, diabetes mellitus, heart failure, history of ischemic stroke, history of hemorrhagic stroke, arrhythmia, and hypertension were not associated with 1-year unplanned readmission
Summary
Evidence regarding the relationship between body mass index (BMI) and 1-year unplanned readmission was limited. erefore, the objective of this research is to investigate whether BMI was independently related to 1-year unplanned readmission in Chinese patients with acute myocardial infarction (AMI) after percutaneous transluminal coronary intervention (PCI) after adjusting for other covariates. Evidence regarding the relationship between body mass index (BMI) and 1-year unplanned readmission was limited. Erefore, the objective of this research is to investigate whether BMI was independently related to 1-year unplanned readmission in Chinese patients with acute myocardial infarction (AMI) after percutaneous transluminal coronary intervention (PCI) after adjusting for other covariates. E target independent variable and the dependent variable were BMI measured at baseline and 1-year unplanned readmission, respectively. E rate of readmission in patients with AMI was 26.14%. Nonlinear relationship was detected between BMI and 1-year unplanned readmission, whose point was 29.3. BMI has a nonlinear relationship with 1-year unplanned readmission in patients with myocardial infarction. E 1-year unplanned readmission rate of overweight patients (BMI > 29.3 kg/m2) has increased significantly.
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