Body Irradiation Using Tomotherapy Helical & Direct Technique Using Radixact for Young and Paediatric Patients

Abstract

Background: We have treated 14 patients of total body irradiation (TBI) in Helical Tomotherapy, out of which 9 are males and 5 are females, age is 5 years to 33 years with acute lymphoblastic leukemia (ALL) remission or acute myeloic leukemia (AML). Total Body Irradiation is an important procedure in the conditioning for Bone Marrow and stem cell transplantation. We present here our treatment technique, treatment planning, delivery and dose verification. Standard Total prescribed dose of target volume 12 Gy in 6 fractions twice daily over 3 days to the whole body with Simultaneous Integrated Boost of 14 Gy/6# to brain. Dose volume constraint for the planning treatment volume (PTV) 95% of prescribed dose is getting by 95% of the volume. Material and Methods: We immobilized the whole body of the patients from Vac-loc and thermoplastic mask for head. We take two computerized tomography (CT) scan for treatment Planning. Result: Average dose D95 to the planning treatment volume was 11.7 Gy corresponding to a mean coverage of the planning treatment volume of 95%. Average dose (D-mean) for the lungs was not exceeding 9 Gy. Conclusions: Total Body Irradiation using helical Tomotherapy is achievable and well tolerated. Each dose distribution is homogeneous and reduce dose to at risk organ.