Abstract

The rectal temperature of dogs was reduced to 27°C and stabilized at this level for a period of at least 3 hours. The heart rate, blood pressure, respiration rate, blood volumes, extracellular volume (thiocyanate space), and total body water (antipyrine space) were recorded during the reduction in temperature and the period of stable body temperature. No change was observed in the mean arterial pressure during any period of hypothermia; the heart rate decreased exponentially during the reduction in body temperature but remained constant during the stable period. Blood volume increased during the initial stages of hypothermia (33°C to 36°C) and remained at this level. Hematocrit and erythrocyte volume followed the same pattern as total blood volume, with no alteration in the plasma volume. There were no shifts in the extracellular or intracellular volumes at any time during the hypothermic state.

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