Abstract
The regulation of body fluid homeostasis requires neural and endocrine control of behavioral, cardiovascular, and renal responses in order to maintain the osmolality and volume of body fluid at levels that are optimal for physiological function. Challenges to body fluid homeostasis result in changes in plasma osmolality and/or the effective circulating blood volume that are both detected by sensors that relay imbalance to the appropriate effector organs; however, plasma osmolality and volume are regulated independently by distinct behavioral and endocrine responses. This chapter focuses on neurohumoral systems that control behavioral, cardiovascular, and renal compensatory mechanisms that maintain body fluid homeostasis.
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