Abstract

Objective: Aim of our study is to investigate physical and chemical structure and properties of body lipids at various anatomical sites. Trial design: A pilot physical and chemical descriptive experimental trial in vitro. Methods and Participants: Adipose tissue in the amount of 252 samples from 36 individuals (17 dead females) at autopsy. The subjects had died from various injuries and were between 36-60 years old. Interventions: Chemical groups and compounds were studied on infrared spectrometry with software, and atomic adsorptive analysis on spectrometer. Elemental chemical analysis of lipids different localization carried out. Research Subject: Chemical elements and compounds. Results: The highest levels of saturated fatty acids and almost all chemical groups and compounds analysed are found in dense atherosclerotic plaque (AP). In those samples, relatively more compounds containing metabolic products were identified (P < 0.05, n = 252). Dense AP contains relatively more saturated and branched hydrocarbon chains, and they have the largest quantities of organic and inorganic elements and compounds in their structure. Conclusions: Human body lipids, especially dense AP, serve as a depot for various organic substances. Once having been formed, the AP has its own pathophysiological role in adsorption of redundant waste products.

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