Abstract
As one of the methods in differentiating so-called Koga's “camouflaged tuberculosis” with the so-called neurosis, the influence of so-called emotional stress (emotions such as anxiety, fear, etc, ) upon the living body, especially upon the anterior pituitary-adrenal cortical system has been studied. Furthermore, as a control experiment, the influence of physical fatigue and malignant neoplasm upon the adrenal cortex, and at the same time the influence of environmental change upon the living body have been observed.1. White rats received ample emotional stress applying Koga's apparatus.2. Muscle exercise proved to be a strong stressor.3. Transplantation of Yoshida's sarcoma became a stressor in white rats, and on the contrary, lead to exhaustion. Administration of cortisone gave a poor influence upon the living body.4. Although laboratory practice may temporarily become a stressor in white rats, it was found that they gradually adapted.5. Since it can be considered that the handling of animals may influence the living body as a so-called emotional stress, special care must be taken in selecting the control value.
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