Bo K. Siesjö, MD, PhD

Abstract

We acknowledge with great sadness the passing of Bo K. Siesjo, MD, PhD, in his 83rd year. He was founder and former director of the Laboratory of Experimental Brain Research, Lund University Hospital, Sweden, and former director of research in the Center for the Study of Neurological Diseases at Queen’s Neuroscience Institute, Honolulu, Hawaii. Dr Siesjo was a giant in the field of brain metabolism, stroke, and tissue injury research, and an international leader in experimental approaches to treat brain diseases. He dedicated decades of his professional career to pioneer the importance of calcium overload and oxygen radical generation in ischemic cell death, as well as pursued them as targets for therapy. He was recognized as an international authority on the regulation of acid-base metabolism in normal and diseased brain, and his passing leaves a large gap in this important area of knowledge. Dr Siesjo has been lauded and celebrated many times over by his colleagues and students, including the Mihara Award (1989), the J. Allan Taylor International Prize in Medicine (1992), The K.J. Zulch Prize (1992), and the Lifetime Achievement Award by the International Society for Cerebral …