Bệnh viện Trung ương Quân đội 108

Abstract

Objectives: To study the relationship between echocardiographic indices of the left atrium with plasma NT-proBNP levels in heart failure patients with preserved ejection fraction. Subjects and methods: 47 patients diagnosed with HFpEF were treated at 108 Military Central Hospital, from June 2020 to June 2021. All patients were tested for NT-proBNP levels and underwent speckle tracking echocardiography according to protocol. Results: The average age was 67.04 ± 12.6 years old and males accounted for a high proportion of 78.7%. There is a positive correlation between left atrial volume index (LAVi) and NT-proBNP (r = 0.373; p = 0.01); strong negative correlation between LA reservoir function (LASr) in 4-chamber view with NT-proBNP (r = 0.610; p < 0.001), moderate negative correlation with LASr in 2-chamber view (r = 0.335; p = 0.014); positive correlation between LA reservoir function (LAScd) in 4-chamber view (r = 0.360; p = 0.013), LA contractile function (LASct) in 4-chamber view (r = 0.438; p = 0.02). Conclusion: Left atrial speckle tracking echocardiographic parameters in 4-chamber and 2-chamber views (LASr, LAScd, LASct), LAVi are related to serum NT-proBNP levels in patients with HFpEF. * Keywords: Left atrium; Speckle tracking; Echocardiography; NT-proBNP.