Abstract
E-mail: Kazemi_f@iasbs.ac.irReceived October 27, 2012, Accepted November 19, 2012In this paper, in addition to introducing efficient method for bromohydrin and bromoether preparation, simple,green and efficient method to C-N bond formation from alkene and N,N'-Dibromo-N,N'-1,2-ethanediyl-bis(p-toluenesulfonamide) [BNBTS] in water was investigated. The reaction between alkenes, β-cyclodexterin, andBNBTS took place in water afterward, by making media basic; it will give the corresponding valuable buildingblocks in good yields (45-79%).Key Words : C-N bond formation, BNBTS, N-bromo sulfonamide, Bromo hydrin, Building blocksIntroductionThe regioselective electrophilic addition to alkenes is ofimportance process in organic synthesis and several meth-odologies have been described in the literature. The trans-formation of alkenes into the corresponding halohydrins andhaloethers is frequently practiced in organic synthesis.
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