BMI, Waist Size, GFR: In African American Blacks

Callender Clive O,Campbell Alfonso L,Apprey Victor,Adesibikan Babwande,Bonney George,Idris-Suleiman Linda,Michael Miriam,Mwendwa Denee T,Ii Larry Keen,Ivy Gabriel,Madhere Serge,Magnus-Lawson Bomi,Gholson Georica,Herren Olga,Hernandez Arturo,Wright Regina Sims

doi:10.23937/2572-4010.1510028

Abstract

Blacks have a greater need for kidney transplants than other American ethnic groups. Overrepresented on kidney transplant waiting lists (13%), they account for 35% of those waiting. Recent studies show that Black live donors are at greater risk for kidney failure, (44%) after donation, compared to other ethnicities. Explanations for these live donation data are few. While diabetic, hypertensive or morbidly obese Blacks are excluded as live donors; those overweight or obese are not.

Highlights

There has been a sustained effort to encourage live kidney donation among Blacks in the past three decades, and organ donation has consistently risen within this community [1,2,3]
Bivariate correlation analyses showed body mass index (BMI) and waist circumference correlated with glomerular filtration rate (GFR) > 130 cc/min. (r = 0.67, p < 0.01 and r = 0.66, p < 0.01, respectively)
Logistic regression analyses revealed that BMI and WC classified obese males were more likely to have a GFR > 130

Summary

Introduction

There has been a sustained effort to encourage live kidney donation among Blacks in the past three decades, and organ donation has consistently risen within this community [1,2,3]. Live kidney donation is a major surgical procedure, complications after surgery are considered minimal Racial/Ethnic differences after kidney donations have been noted with African Americans (AA) experiencing increased risks for hypertension, diabetes mellitus, and chronic kidney disease compared to White and Hispanic donors [4]. Being obese and morbidly obese carries increased risk, up to a four-fold increase, for developing renal disease and chronic renal failure [8,9]. This is present among donors who are overweight and severely obese, [10]. GFR and renal plasma flow rate increase Another explanation suggests that excessive visceral adiposity physically compresses the kidneys and increases renal-pressure natriuresis [15]

Methods

Results

Conclusion