Abstract

BMI and mortality: the limits of epidemiological evidence

Highlights

  • 3 O’Donnell MJ, Chin SL, Rangarajan S, et al, on behalf of the INTERSTROKE investigators

  • Pooled analyses benefit from the use of harmonised methods but, unlike meta-analyses, are not generally based on systematic review

  • Prespecified analyses of never smokers without pre-existing chronic disease, excluding the first 5 years of follow-up, are presented for about 3·9 million participants and about 386 000 deaths occurring in 189 studies

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Summary

Introduction

3 O’Donnell MJ, Chin SL, Rangarajan S, et al, on behalf of the INTERSTROKE investigators. Reduction of exposure to these risk factors at a population level (for example, reducing salt and sugar content in processed foods at the manufacturing stage) has been shown to be beneficial for cardiovascular disease and overall health.[5,6] Compelling evidence shows that taxation on these hazardous behavioural factors could represent a valuable strategy to improve health.[7,8,9,10,11] Revenue from these taxations could and should be used to fund primary preventive programmes and research on stroke and other major non-communicable diseases.

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Conclusion
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