Abstract
The Pharmaceutical Journal of Sri Lanka is the official scientific publication of the Pharmaceutical Society of Sri Lanka. Authors are invited to submit articles throughout the year, and if accepted after a blinded peer review process, will be published online in one of the two issues published each year. The journal including both issues will be printed only once a year. The Pharmaceutical Journal of Sri Lanka aims at providing an avenue for publications by pharmacy undergraduates, university academics, pharmacists and pharmaceutical scientist of Sri Lanka and the South Asian region. The journal accepts original research work either as a full research paper or as a short communication, review, brief report, special communication, commentary, case study and other categories of articles related to pharmaceutical sciences. Articles are accepted on the understanding that they have not been published elsewhere.
Highlights
In the healthy human body, fluid is distributed between intracellular and extracellular compartments.[1]
Lymph capillaries are more profusely intertwined alongside the finer capillary tufts of the blood circulatory system, an arrangement that facilitates reabsorption of interstitial fluid from the tissues leading to formation of lymph
The right lymphatic duct, and the thoracic duct enter the blood circulation at the right subclavian and left subclavian veins discharging the lymph into the blood circulatory system (Figure 1). [6, 7]
Summary
In the healthy human body, fluid is distributed between intracellular and extracellular compartments.[1]. The main objective of this review article is to conceptualize the bloodless circulatory systems (BSCS) with novel drug delivery potential. These systems are quite intricate to explain under conventional drug absorption, distribution, metabolism and elimination (ADME) as applied to blood circulatory system. Emerging out of the systemic blood circulatory system through a molecular filtration process these systems circulate in loops and return back, except axoplasmic circulation in nerve axons which is an intricate independent system. The nerve axoplasma circulatory system, neglected until recently has come under a flurry of research activity presently There is good scope for physical manipulations and surgical interventions too
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