Abstract
AbstractTwo cephalopods, Sepia officinalis L. and Loligo vulgaris Lam., have been investigated for soluble inhibitors of anti human blood‐group agglutinins. Only a weak inhibition was observed with respect to human anti‐A isoagglutinin. In the agar‐gel double diffusion test, however, the test substances showed a very strong precipitation reaction with heterophile anti‐A from snails. The precipitation lines were identical with that of A substance from peptone. The A‐like substances found were identified as glycoproteins containing terminal, non‐reducing bound α‐N‐acetyl‐D‐galactosamine. The biological importance of these macromolecules is discussed with particular reference to their reactive site.
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