Abstract

We read with much interest the article by Chi et al[1][1] in the March 2019 issue of the American Journal of Neuroradiology , “Alterations in Blood-Brain Barrier Permeability in Patients with Systemic Lupus Erythematosus.” Reportedly, dynamic contrast-enhanced (DCE) imaging supports the

Highlights

  • We read with much interest the article by Chi et al[1] in the March 2019 issue of the American Journal of Neuroradiology, “Alterations in Blood-Brain Barrier Permeability in Patients with Systemic Lupus Erythematosus.”

  • Dynamic contrast-enhanced (DCE) imaging supports the hypothesis that patients with systemic lupus erythematosus have increased blood-brain barrier (BBB) permeability, in the hippocampus, compared with other brain regions.[1]

  • Vb corresponds to the volume of vessels per volume of tissue

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Summary

Introduction

We read with much interest the article by Chi et al[1] in the March 2019 issue of the American Journal of Neuroradiology, “Alterations in Blood-Brain Barrier Permeability in Patients with Systemic Lupus Erythematosus.”. Dynamic contrast-enhanced (DCE) imaging supports the hypothesis that patients with systemic lupus erythematosus have increased blood-brain barrier (BBB) permeability, in the hippocampus, compared with other brain regions.[1] some technical issues in the current study may limit its conclusions.

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