Abstract

Summary Blood volume measurements using Cr 51 and I 131 were carried out before and after severe, gradually corrected blood loss in unanesthetized sheep. Reversibly and irreversibly shocked animals were studied. Blood volume and total body hematocrit remained unchanged; large vessel hematocrit rose, and F cells ratio fell. Excessive plasma skimming in the small vessels is suggested as the possible cause of this phenomenon. The unpredictability of F cells ratio in posthemorrhagic states and the fallacy inherent in the use of a single label in blood volume determinations is reemphasized.

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