Abstract
In patients who are treated with diuretics, blood urea nitrogen (BUN) to serum creatinine (Scr) ratio is frequently used to evaluate intravascular volume status. We aimed to investigate the correlation between BUN to Scr ratio and invasive hemodynamic assessment of intravascular volume status. Data from patients who underwent right heart catheterization (RHC) at our center from 2008 to 2011 were reviewed. We obtained BUN, Scr and BUN to Scr ratio from Lab collected within 24 hour from the RHC. We obtained right atria (RA) pressure and pulmonary capillary wedge pressure from the RHC. A total of 501 patients were included in the analysis. 213 patients had BUN/Cr ratio more than 20. There was no correlation between high BUN to Scr ratio with RA pressure. Linear regression analysis was used, adjusted R-squared = 0.0157. High BUN to Scr ratio did not predict intravascular volume status in our population, and this could be due to rapid diuresis, and diuretics therapy in patients with symptomatic heart failure should not be based on this ratio.
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
