Blood transfusion therapy
 in cancer patients: modern aspects

Abstract

Relevance: Anemia is a common syndrome in cancer patients, and blood transfusion is the most common
 treatment for anemia. Anemia and blood transfusion
 are associated with worse clinical outcomes. The efficacy and safety of different blood transfusion strategies
 are unclear.
 The purpose was to analyze current blood transfusion strategies in oncology.
 Results: In most clinical situations, a restrictive
 strategy showed efficacy and safety. However, low
 perioperative hemoglobin level is associated with increased mortality and complication rates. Several clinical trials demonstrated the benefits of liberal strategy;
 it may be due to comorbidities and low compensatory
 ability.
 Conclusion: In cancer patients, anemia is associated with worse clinical outcomes. Therefore, modern
 blood transfusion therapy strategies in oncology follow
 the restrictive approach, taking into account possible
 blood transfusion complications. Cancer patients are a
 complicated patient category and require an individual
 approach to postoperative anemia treatment.