Blood supply to the uterus and ovaries in healthy women and patients with ovarian insufficiency

Abstract

The aim of this study was to investigate the relation between ovarian blood flow, folliculogenesis and sex-steroid production during normal menstrual cycle and in women with ovarian failure. Ten healthy women and 40 patients with ovarian failure underwent hormonal assays (follicle-stimulating, luteinizing hormones, estradiol, progesterone, prolactine, testosterone) and ultrasound examination of the uterus and ovaries with color Doppler ultrasonography of the uterine and ovarian vessels on the 3 -5th, 11- 13th, 17- 19th and 21 -23rd days оf menstrual cycle. Intraovarian blood flow of the ovary carrying the predominant follicle in healthy women appeared more active than in conrdlateral ovary on the 3-5th days of the cycle. Inpatients with ovarian failure no difference was detected between the ovaries during the periods in question. Ovarian and uterine blood flow inpatients with the ovarian failure was less intensive comparingwith healthy women. Positive correlation between uterine blood flow and estradiol concentration in serum was revealed.