Blood Sugar Management in Delivery for Pregnant Women With Abnormal Glucose Metabolism Associated With Neonatal Hypoglycemia

Abstract

Objective To analyze the relationship between maternal blood glucose level and the incidence of neonatal hypoglycemia, and evaluate ways and significances of maternal blood glucose management of gestational diabetes mellitus(GDM)women during labor. Methods A retrospective analysis was conducted on 435 cases from August 2002 to October 2007 of singleton pregnancy with abnormal gestational glucose tolerance, whose blood glucose levels were monitored during labor, were subdivided into 206 cases with the gestational impaired glucose tolerance group(GIGT group),136 cases and 93 cases with the gestational diabetes mellitus Al(GDMA1 group)and A2 group(GDMA2 group), respectively. Results The morbidity of neonatal hypoglycemia in GIGT group, GDMAl group and GDMA2 group was 2.9%,2.9% and 1.1%,respectively(P=0.602). Within the 3 gestational groups of abnormal glucose metabolism, no significant difference was found in the incidence of neonatal hypoglycemia between women with the blood glucose 0.05)]. No correlation was detected between the immediate neonatal blood glucose value at birth and maternal mean blood glucose during labor in 3 groups(P=0. 260, 0.861,0.296). Conclusion With strict glycemia control for pregnant women and appropriate management of newborns, maternal hyperglycemia of the women with gestational diabetes mellitus during labor has limited effect on the level and the incidence of neonatal hypoglycemia. Blood glucose assay and immediate feed for high risk neonates might have more clinical importance. Key words: gestational diabetes mellitus; labor; blood glucose; neonatal hypoglycemia