Blood Regeneration in Severe Experimental Anemia. Influence of Inorganic Elements.

Abstract

We have recently reported in these Proceedings1 a rather startling reaction to the inorganic ash of liver, kidney and apricots. This ash incorporated in a standard anemia diet2 given to dogs kept constantly anemic by bleeding will effect a notable increase in blood hemoglobin production above control periods. This may amount to 30 to 50 gm. hemoglobin per 2-week period.We have made various analyses of these ashes and from such data have made various synthetic ash compounds, but such synthetic mixtures so far have not proved to be potent. These experimental data will be published in due time.We wish to report briefly our findings when these dogs are given various simple salts added to the standard ration. It is apparent that in the doses given iron is more potent than either copper or zinc.These observations dealing with copper salts are of considerable interest when contrasted with the recent reports of Hart, S teen-bock, Waddell and Elvehjem,3 who report a distinctly favorable reaction to copper salts an...