Abstract

This study sought to evaluate the relationship between blood pressure variability and left ventricular mass index (LVMI) in children with true ambulatory hypertension. We conducted a cross-sectional survey among 115 children who were consecutively referred for evaluation of hypertension to our University Children’s Hospital. The calculated blood pressure variability (BPV) measures were 24-h average real variability (ARV) and 24-hour weighted SD (wSD). LVMI was estimated by M-mode echocardiography using Devereux’s formula and indexed for height.
 A total of 35 children had true ambulatory hypertension. We found no correlation between 24-hour ARV and wSD with LVMI. On the other hand, partial correlation analysis revealed statistically significant and inverse correlation between 24-hour ARV and LVMI, controlling for body mass index (r = -0,516; P = 0.002).
 Contrary to previous studies, our results indicate inverse association of LVMI and BPV as expressed by ARV in a population of true hypertensive children.

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