Blood pressure variability analysis enhances risk stratification in chronic heart failure

Matthias Goernig,Andreas Voss,Uwe Leder,Rico Schroeder,Hans Reiner Figulla,Robby Kleindienst

doi:10.7243/2052-4358-2-5

Abstract

Introduction Outcomes related to chronic heart failure (CHF) remains very poor: mortality is related to its severity ranging from 5 to 10% in patients with mild to 30-40% in severe cases [1,2]. The main cause of death in CHF is related to arrhythmic events and these patients are also at risk

Highlights

Outcomes related to chronic heart failure (CHF) remains very poor: mortality is related to its severity ranging from 5 to 10% in patients with mild to 30-40% in severe cases [1,2]
We separated our CHF patients in two groups: a group with low ejection fraction (EF) (EF-) when the EF cut-off value was below 40% and a group with preserved EF (EF+) when the cut-off value was equal or higher than 40%
There are no significant differences in the clinical parameters age, gender, BMI and medical treatment and significant differences in NYHA class, LVEDD, LVEDP and QRS duration

Summary

Introduction

Outcomes related to chronic heart failure (CHF) remains very poor: mortality is related to its severity ranging from 5 to 10% in patients with mild to 30-40% in severe cases [1,2]. Evidence suggests that implantable cardioverter defibrillators (ICD) reduce total mortality in CHF but may be cost-effective in some subgroups of patients at high risk [3]. Further research is needed for risk stratification of patients in whom ICD are most likely to be clinically and cost-effective. Clinical importance of autonomic control became apparent since the late 1980s when it was confirmed that HRV was a strong and independent predictor of mortality following an acute myocardial infarction. With the availability of high frequency 24-h multi-channel electrocardiographic recorders, HRV has the potential to provide additional valuable insight into physiological and pathological conditions and to enhance risk stratification in different cardiac diseases [4]. Is reflecting clinical relevance of BPV in cardiology with respect of autonomic control physiology and cardiac risk stratification [16]

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