Abstract

Electronic cigarettes (ECs) are battery-operated devices designed to vaporise nicotine, which may help smokers with quitting or reducing their tobacco consumption. No data is available regarding the health effects of ECs use among smokers with arterial hypertension and whether regular use results in blood pressure (BP) changes. We investigated long-term changes in resting BP and level of BP control in hypertensive smokers who quit or reduced substantially their tobacco consumption by switching to ECs. A medical records review of patients with hypertension was conducted to identify patients reporting regular daily use of ECs on at least two consecutive follow-up visits. Regularly smoking hypertensive patients were included as a reference group. A marked reduction in cigarette consumption was observed in ECs users (n = 43) though consumption remained unchanged in the control group (n = 46). Compared to baseline, at 12 months (follow-up visit 2) decline in cigarette consumption was associated with significant reductions in median (25th-, 75th-centile) systolic BP (140 (134.5, 144) to 130 (123.5, 138.5) mmHg; p < 0.001) and diastolic BP (86 (78, 90) to 80 (74.5, 90) mmHg; p = 0.006). No significant changes were observed in the control group. As expected, decline in cigarette consumption in the ECs users was also associated with improved BP control. The study concludes that regular ECs use may aid smokers with arterial hypertension reduce or abstain from cigarette smoking, with only trivial post-cessation weight gain. This resulted in improvements in systolic and diastolic BP as well as better BP control.

Highlights

  • Smoking is the leading cause of preventable premature mortality in the world

  • A total of 89 (50 male, 39 females) regular smokers with a diagnosis of hypertension and on anti-hypertensive drugs at baseline were studied. They had either pre-hypertension, or grade 1 or 2 hypertension according to 2013 ESH/ESC criteria [24] despite taking at least three antihypertensive agents

  • We illustrate for the first time the utility of Electronic cigarettes (ECs) as a bridge in reducing cigarette consumption in smokers with arterial hypertension

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Summary

Introduction

Smoking is the leading cause of preventable premature mortality in the world. Death is mainly caused by ischemic heart disease, stroke, lung cancer, and the catastrophic complications of advanced stage chronic obstructive pulmonary disease [1]. Public Health 2016, 13, 1123; doi:10.3390/ijerph13111123 www.mdpi.com/journal/ijerph

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