Abstract
Blood nitrite and nitrate concentrations were measured after oral and intravenous administration of glyceryl trinitrate at 1.0 mg./Kg. in rabbits. Nitrate and nitrite blood concentrations attained peak concentrations in 90–120 min. after oral administration and slowly returned to control levels. Nitrate and nitrite blood concentrations decreased slowly after intravenous administration of glyceryl trinitrate, then fell rapidly after 60 min. Blood nitrate concentrations were twice the blood nitrite concentrations 60 min. after either oral or intravenous administration of glyceryl trinitrate.
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