Abstract
Cross-sectional survey of the population aged 25-45 in Novosibirsk was carried out. The study included 1439 people (656 men and 783 women). Within the framework of the complex survey program, thestandardized epidemiological questionnaire of Rose (WHO, 1984) was used. Blood levels of total cholesterol (total C), triglycerides (TG), low and high density lipoprotein cholesterol (LDL-C, HDL-C) were determinate by biochemical methods. For all lipid indicators, significant differences were found between men and women. The levels of total C, TG and LDL-C were significantly higher, and the level of HDL-C was lower in men, than in women. According to the Rose questionnaire, out of 1439 people included in the study, 12 patients (0.8%) had AP (75% women). In persons with AP, blood levels of TG were 1.8 times higher, and the levels ofHDL-C in blood was 1.2 times lower compared to persons without AP. Univariate analysis of associations of AP with CHD risk factors showed that the chance of developing angina pectoris in the population of 25-45 years was significantly increased in individuals with high blood TG levels (OR 3,515, DI 1,106-11,168, p = 0.039) and low HDL-C (OR 1,203, DI 1,054-1,372, p = 0.006). A natural, although statistically not significant (OR 3,165, p=0,055, due to the small number of groups with AP) increasing in thechance ofdeveloping AP in hypertension was detected. In the young population of 25-45 years in Novosibirsk, elevated blood levels of TG, reduced levels of HDL-C, and hypertension were associated with AP, according to Rosecardiological questionnaire, which underlines the importance of conducting screening surveys of the young population to improve effective prevention and treatment of diseases.
Highlights
Распространенность стенокардии напряжения (СН) по опроснику Роуза увеличивалась с возрастом (0,7 % у пациентов в возрасте от 40 до 49 лет и 7,1 % у лиц в возрасте 70 лет и старше) и ассоциировалась с сердечно-сосудистыми ФР, за исключением курения
Результаты показали, что шанс развития СН в общей популяции 25–45 лет достоверно повышен у лиц с высоким уровнем ТГ крови, а также связан с более старшим возрастом
Шанс развития стенокардии напряжения (СН) в общей популяции 25–45 лет достоверно повышен у лиц с высоким уровнем ТГ крови (отношение шансов (ОШ) =3,515, р=0,039), с низким ХС ЛПВП (ОШ=1,203, р=0,006), а также у лиц более старшего возраста (ОШ=1,014, р=0,003)
Summary
Настоящее исследование было проведено с целью изучения распространенности стенокардии напряжения (СН) по стандартизованному эпидемиологическому опроснику Роуза в молодой популяции 25–45 лет г. Распространенность СН по опроснику Роуза составила 2,6 % (95 % ДИ: 2,1–3,1 %) и была выше у женщин (2,9 %), чем у мужчин (2,2 %). Распространенность СН по опроснику Роуза увеличивалась с возрастом (0,7 % у пациентов в возрасте от 40 до 49 лет и 7,1 % у лиц в возрасте 70 лет и старше) и ассоциировалась с сердечно-сосудистыми ФР, за исключением курения.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
