Abstract

A method employing safe tracer doses of I 131 and a sensitive windowless counter is described which permits measurement of the total and protein-bound radioactivity in 1 ml. of plasma seventy-two hours after oral administration of the tracer dose. The results in a series of 187 euthyroid and 123 hyperthyroid subjects are presented. In these 310 cases only three discordant values were encountered, results better than were obtained with any other test for hyperthyroidism employed. The method requires the use of a windowless counter or counter of similar sensitivity but if this is available the technic is simple and specific.

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