Abstract

ObjectivesThe aim of this study is to describe blood lead levels (BLLs) and the prevalence of elevated blood lead levels (EBLLs) in children aged 0–6 years old and to analyze the BLL trend in children from 2009 to 2013 in China.MethodsA total of 124,376 children aged 0–6 years old were recruited for this study from January 1st 2009 to December 31st 2013. Their blood lead levels were analyzed using atomic absorption spectrometry.ResultsThe median BLL was 64.3 μg/L (IQR: 49.6–81.0), and the range was 4.3–799.0 μg/L. Blood lead levels were significantly higher in boys (66.0 μg/L) than in girls (61.9 μg/L) (P<0.001). The overall prevalence of BLLs≥100 μg/L was 10.54% in children aged 0–6 years in Hunan Province. Between 2009 and 2013, the prevalence of EBLLs (≥100 μg/L) decreased from 18.31% to 4.26% in children aged 0–6 years and increased with age. The prevalence of EBLLs has dramatically decreased in two stages (2009–2010 and 2012–2013), with a slight fluctuation in 2010 and 2011.ConclusionsBoth BLLs and the prevalence of EBLLs in children aged 0–6 years old declined substantially from 2009 to 2013 in Hunan Province; however, both remain at unacceptably high levels compared to developed countries. Comprehensive strategies are required to further reduce blood lead levels in children.

Highlights

  • It is well known that there is no safe blood lead level (BLL) in children

  • Blood lead levels were significantly higher in boys (66.0 μg/L) than in girls (61.9 μg/L) (P

  • The prevalence of elevated blood lead levels (EBLLs) has dramatically decreased in two stages (2009–2010 and 2012–2013), with a slight fluctuation in 2010 and 2011

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Summary

Introduction

It is well known that there is no safe blood lead level (BLL) in children. Many studies have demonstrated that lead exposure is related to the risk of behavioral and intellectual deficits, hypertension, nephropathy and infertility [1,2,3,4,5,6,7]. The National Toxicology Program (NTP) concluded that the presence of lead in blood at BLL

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