Abstract

Abstract Objectives Lead exposure in children contributes to 600,000 new cases of intellectual disabilities every year with maximum occurrence in developing countries. Currently limited information is available on the blood lead level (BLL) in children of India. The aim was to estimate BLL in the school going children of local population of Jodhpur. Methods Four hundred twenty-six primary school children of government and private schools participated in this cross sectional study. Information regarding possible lead exposure was collected. BLL was estimated on Lead Care II analyser (Magellan Diagnostics, USA). Results The mean and median BLL were 4.25 ± 1.75 μg/dL (<3.3–22.6 μg/dL) and 3.5 μg/dL (Inter Quartile Range 0.9). BLL was higher in children of illiterate mothers, those residing near traffic dense areas, urban region and studying in government schools of urban region. Conclusions BLL in children residing in Jodhpur is much higher in comparison to western counterparts. Screening and awareness programs regarding potential sources of lead exposure can help in improving BLL.

Highlights

  • The goal of the ATSDR Case Studies in Environmental Medicine (CSEM) series is to increase the primary health care provider’s knowledge of hazardous substances in the environment and to promote medical practices that aid in the prevention, evaluation and care of potentially exposed patients

  • Subclinical neurological effects may occur at lower blood lead level (BLL) — at or below the regulatory standard of 10 μg/dL, in some cases — and it may not be possible to detect them on clinical examination at the time of the exposure or peak BLLs

  • This study addressed most of the deficiencies of the prior studies and demonstrated a statistically significant dose-response relationship between maternal BLLs and risk for spontaneous abortion [Borja-Aburto et al 1999]

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Summary

Disclosure

In compliance with continuing education requirements, all presenters must disclose any financial or other associations with the manufacturers of commercial products, suppliers of commercial services, or commercial supporters as well as any use of unlabeled product(s) or product(s) under investigational use. CDC, our planners, and the presenters for this seminar do not have financial or other associations with the manufacturers of commercial products, suppliers of commercial services, or commercial supporters. This presentation does not involve the unlabeled use of a product or product under investigational use. There was no commercial support for this activity

Introduction
Key Points
What test would you order to confirm or rule out your diagnosis?
Which of the following statements regarding environmental lead is correct?
What are the OSHA Standards for Lead Levels?
12. What is the approximate half-life of lead in the blood of an adult?
16. What is the identified threshold or safe level of lead in blood?
19. Which of the following is not a typical sign or symptom of lead toxicity?
26. When is ongoing monitoring of BLLs indicated?
27. BLLs that increase may indicate which of the following?
Which of the following is true about organic lead in the United States?
Which of the following is NOT considered a potential source of lead exposure?
12. What is the CPSC regulatory limit value for lead in paint?
15. What is the approximate half-life of lead in the blood of an adult?
20. What is the identified threshold or safe level of lead in blood for children?
29. When is ongoing monitoring of BLLs indicated?

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