Blood glucose level during hemodialysis in non-diabetic patients with end-stage renal disease

Abstract

Objective To observe the level of blood glucose during hemodialysis in non-diabetic patients with end-stage renal disease. Methods Twenty non-diabetic patients were collected and assigned to group I (n=11, food intake was prohibited in the process of hemodialysis) and group II (n=9, food intake was allowed at 1.5 to 2.0 hours after hemodialysis). During hemodialysis , the blood glucose at 0, 0.5, 1.0, 2.0 and 4.0 hours was measured.The glucose of waste dialysate was measured in all the patients. Results Overt hypoglycemia was occurrent in none of the patients during hemodialysis, although two patients presented occult hypoglycemia in the fasting group.In the food taken group, the blood glucose rised gradually and dropped in the other group.In the food taken group, the loss of glucose in waste dialysate was (17.70±6.33)g.In the fasting group, the loss of glucose in waste dialysate was (15.43±8.52)g. There was no significant difference between the two groups. Conclusion There may be the risk of hypoglycemia during hemodialysis in non-diabetic renal patients.The loss of glucose during hemodialysis could be the main reason of hypoglycemia.The use of dialysate with glucose can reduce the risk of hypoglycemia in non-diabetic patients with end-stage renal disease. Key words: Non-diabetic renal disease; Hemodialysis; Glucose loss; Hypoglycemia; Dialysate