Abstract

Blood flow and progestin levels in corpora lutea and in the ovaries minus corpora lutea (interstitial gland) were determined in pregnant New Zealand rabbits having one nongravid uterine horn. Corpora lutea weight, interstitial gland weight, progestin levels in the ovary and blood flow in the corpora lutea and interstitial gland were similar in the 2 ovaries between days 5 and 25. The ratio of 20a-hydroxypregn- 4-en-3-one (20a-OH) to progesterone was 4-16 times higher in the interstitial gland than in the corpora lutea. Blood flow rates in the corpora lutea were highest at day 10, decreasing significantly at later stages. Blood flow rates in the interstitial gland were relatively constant throughout pregnancy. These results indicate that one nongravid horn has no differential or local effect on the ipsilateral ovary during pregnancy in the rabbit. (Endocrinology 88: 821, 1971)

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