Abstract
Operation, in cases of subacute bacterial endarteritis superimposed on patent ductus arteriosus, necessitates direct exposure of the pulmonary artery and aorta.1, 2, 3 This offers an opportunity to take blood cultures directly from the above structures.In a recent case, 14 ml of blood were drawn simultaneously from both the pulmonary artery and the aorta. Agar-plate cultures of the blood taken from the pulmonary artery revealed innumerable colonies of Streptococcus viridans. The aortic specimen contained 51 colonies per ml of blood. These quantitative determinations indicate that the bacterial content of the blood entering the lungs differs from that of the blood leaving the lungs (and traversing only the left side of the heart.).Heretofore the existence of a pulmonary protective barrier, which removes infective material from the circulating blood, has been demonstrated directly only in experimental animals.4-9 Furthermore, in cases of subacute bacterial endarteritis superimposed on patent ductus arterios...
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