BLOOD CHEMISTRY PARAMETERS IN DOGS WITH ACUTE GASTRIC DILATION SYNDROME DURING THE PREOPERATIVE PERIOD

Abstract

Acute gastric dilation syndrome is a condition that occurs with a significant increase in the stomach volume, which can also beaggravated by twisting the stomach around its axis (gastric torsion). Acute dilation syndrome and gastric torsion is deadly conditions that require immediate veterinary care and intensive therapy. Mortality from this pathology ranges from 10 to 50%, most of the fatal cases occur during postoperative period, and possible complications can affect almost all body systems. The purpose of the presented study was to evaluate and analyze the most common changes in blood biochemical parameters in dogs with acute gastric dilation syndrome, as well as a retrospective review of methods for choosing the resolution of the acute gastric dilation syndrome (surgical intervention or gastric intubation intubation and lavage). Based on the data obtained, a statistical analysis was carried out in order to identify the most prognostically significant parameters. During the study, the regularities of the choice of the treatment method were revealed – for dogs with a live weight of more than 33 kg, in 80% of cases, surgical intervention with subsequent gastropexy was chosen as treatment method. The survival rate of dogs with the choice of surgery as treatment method was 60% (n=10), and for dogs with probing and gastric lavage as treatment method – 50% (n=10). There were also significant (p<0.05) increases in total bilirubin levels and aspartate aminotransferase activity in the group of dogs with a fatal outcome (n=9) when compared with the group of dogs with a benign outcome (n=11). The activity of aspartate aminotransferase in the group of dogs with a benign outcome was 111.52 ± 69.34 IU/l, and in the group of dogs with a fatal outcome 270.46 ± 179.11 IU/l. The total bilirubin level was 3.27 ± 1.19 μmol/l and 5.34 ± 2.31 μmol/l, respectively.