Abstract
Summary.Two groups of patients were submitted to electric convulsive therapy, one without pre‐treatment (ECT) and the other after administration of thiopentone and succinylcholine (modified ECT). After ECT, there was a large increase in the blood level of catecholamines (noradrenaline+adrenaline), of factor VIII and of plasminogen activator. After modified ECT, the release of catecholamines and of factor VIII was significantly reduced, but hyperfibrinolysis took place as in ECT. These results suggest that while catecholamines are probably not responsible for plasminogen activator release during stress, adrenergic mediation of the concomitant increase in factor VIII is highly probable.
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