Abstract

A man with a primary mediastinal choriocarcinoma is described. Abnormal levels of carcinoembryonic antigen, Regan isoenzyme, and human chorionic gonadotrophin were present in his blood. The levels of all three tumour-associated antigens, followed throughout the patient's course, accurately reflected disease activity as influenced by chemotherapy. Tumour-associated antigens, such as the ones measured in this patient, may provide useful blood indicators of disease activity in certain patients with cancer.

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