Abstract

Leishmaniosis includes a set of diseases produced by protozoan parasites of the genus Leishmania by invasion of the mononuclear phagocyte system of mammalian hosts. Different studies performed in human and canine leishmaniosis have reported that there is an increase in the biomarkers of oxidant status and a decrease in the biomarkers of antioxidant defense, causing an imbalance among oxidants and antioxidants and thus showing that the oxidative damage plays an important role in both diseases. In this chapter the main changes in blood biomarkers of oxidative stress occurring in human and canine leishmaniosis are discussed.

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