Abstract

Blockchain (BC) and Machine learning (ML) technologies have been investigated for potential applications in medicine with reasonable success to date. On the other hand, as accurate and early diagnosis of skin lesion classification is essential to gradually increase the survival rate of the patient, Deep-Learning (DL) and ML technologies were introduced for supporting dermatologists to overcome these challenges. This study designed a Blockchain Assisted Homomorphic Encryption Approach for Skin Lesion Diagnosis using an Optimal Deep Learning (BHESKD-ODL) model. The presented BHESKD-ODL model achieves security and proper classification of skin lesion images using BC to store the medical images of the patients to restrict access to third-party users or intruders. In addition, the BHESKD-ODL method secures the medical images using the mayfly optimization (MFO) algorithm with the Homomorphic Encryption (HE) technique. For skin lesion diagnosis, the proposed BHESKD-ODL method uses pre-processing and the Adam optimizer with a Fully Convolutional Network (FCN) based segmentation process. Furthermore, a radiomics feature extraction with a Bidirectional Recurrent Neural Network (BiRNN) model was employed for skin lesion classification. Finally, the Red Deer Optimization (RDO) algorithm was used for the optimal hyperparameter selection of the BiRNN approach. The experimental results of the BHESKD-ODL system on a benchmark skin dataset proved its promising performance in terms of different measures.

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