Abstract
The majority of tumor-associated macrophages exhibit the M2 phenotype, which is an important determinant of tumor development and metastasis. Reducing the number of intratumoral M2 macrophages is an urgent task. It has been revealed that blockade of glycolysis by sodium oxamate or the glutamine-free medium both suppresses the ability of high-metastatic (LLC) and low-metastatic (LLCR9) Lewis lung carcinoma cells to macrophage reprogramming into the M2 phenotype.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
