Abstract
AbstractBisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare, serious complication of bisphosphonate therapy. We report here a 69-year-old man with a history of multiple myeloma and 5 years of adjuvant zoledronate therapy presenting with loss of light perception, proptosis, ptosis and impaired abduction of the right eye. This patient was found to have developed an unusually severe presentation of osteomyelitis of the skull base in the setting of BRONJ that ultimately led to unilateral blindness. In this extreme case of bisphosphonate-related osteonecrosis of the skull base, we reveal the importance of early identification and treatment of these lesions. This is the first description of BRONJ-induced blindness.
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Schedule a callMore From: Journal of Neurological Surgery Part B: Skull Base
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