Abstract
Malakoplakia, an anecdotal reactive granulomatous lesion, is a rare pathologic entity but relatively more common in genitourinary tracts. Here we report a case of malakoplakia in the urinary bladder in systemic sclerosis. The patient was a 66-year-old female treated with long-term corticosteroid and cyclophosphamide. She presented with gross hematuria, and cystoscopy and biopsy revealed malakoplakia. There was no tumor and the stains for infectious organism were all negative. To the best of our knowledge, this is the first case report of malakoplakia in a systemic sclerosis patient.
Highlights
Introduction and BackgroundSystemic sclerosis is an uncommon connective tissue disease involving skin and vessels, affecting all systems of the body
We report a case of malakoplakia in the urinary bladder in systemic sclerosis
She presented with gross hematuria, and cystoscopy and biopsy revealed malakoplakia
Summary
Introduction and BackgroundSystemic sclerosis is an uncommon connective tissue disease involving skin and vessels, affecting all systems of the body. Malakoplakia, an anecdotal reactive granulomatous lesion, is a rare pathologic entity but relatively more common in genitourinary tracts. We report a case of malakoplakia in the urinary bladder in systemic sclerosis. She presented with gross hematuria, and cystoscopy and biopsy revealed malakoplakia.
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