Abstract

Here we describe a rare case of a 48-year-old woman with a previous history of malignant melanoma (pT2a pathological stage, IB clinical stage) occurring about five years previously. She complained of abdominal pain and pelvic discomfort, diagnosed as a consequence of a bilateral ovarian solid masses completely occupying the recto-uterine space. She underwent laparotomy surgery with total hysterectomy and bilateral salpingo-oophorectomy. Gross examination of the excised material revealed an unusual grey-black bilateral ovarian tumor; a histopathological diagnosis of ovarian bilateral metastatic melanoma was made. Imaging study (CT/MRI) did not reveal metastasis in other zones of the body. Melanoma metastasis usually affects the skin, liver, brain and lungs, and rarely gynecological localizations. On the other hand, most bilateral ovarian tumors are comprised of serous carcinoma, mature teratoma and gastrointestinal carcinoma metastasis. Exceptionally, primary ovarian melanoma may arise in mature ovarian cystic teratomas.

Highlights

  • Section of Pathology, Department of Emergency and Organ Transplantation, University of Bari, Obstetrics and Gynecology Unit, Department of Biomedical Sciences and Human Oncology, Abstract: Here we describe a rare case of a 48-year-old woman with a previous history of malignant melanoma occurring about five years previously

  • Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations

  • A 48-year-old woman was referred to our hospital with a previous history of melanoma occurring about five years previously (2015)

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Summary

These are mostly endometrials

These are mostly endometrials [1,2]. Secondary breastbreast involvement remains exexceptional of ovarian metastases of malignant have been ceptional [3].[3]

The distinction betweenovarian a primary ovarian malignant in the Literature
Available data sugovarian melanoma in mature ovarian teratomas
Uveal Melanoma
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